The TBC1D17 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to TBC1D17. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The TBC1D17 antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known